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Article

ALS-Linked VapB P56S Mutation Alters Neuronal Mitochondrial Turnover at the Synapse.

The Journal of neuroscience : the official journal of the Society for Neuroscience - 28 Aug 2024

Wong Hiu-Tung C, Lang Angelica E, Stein Chris, Drerup Catherine M

Abstract excerpt

Mitochondrial population maintenance in neurons is essential for neuron function and survival. Contact sites between mitochondria and the endoplasmic reticulum (ER) are poised to regulate mitochondrial homeostasis in neurons. These contact sites can facilitate transfer of calcium and lipids between the organelles and have been shown to regulate aspects of mitochondrial dynamics. Vesicle-associated membrane...

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Identifiers

PMID: 39054069
DOI: 10.1523/JNEUROSCI.0879-24.2024
PMCID: PMC11358610

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ALS-Linked VapB P56S Mutation Alters Neuronal Mitochondrial Turnover at the Synapse.PMID 39054069Read ↗

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