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Article

[Acquisition of the drug resistance and Helicobacter pylori gene mutation].

Nihon rinsho. Japanese journal of clinical medicine - 1 Dec 2009

Okimoto Tadayoshi, Murakami Kazunari

Abstract excerpt

The currently recommended regimen in Japan is a proton pump inhibitor-based triple therapy with two of the antibiotics between clarithromycin, amoxicillin and metronidazole. However, recent years have witnessed a decrease in the rate of eradication due to antimicrobial resistance. Resistance mechanisms of H. pylori are explained by the occurrence of mutations in genomic genes, which may correspond to the 23S rRNA...

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PMID: 19999127

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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