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Interferon-induced protein 44 ( IFI44 ) and interferon regulatory factor 4 ( IRF4 ) gene expression in rheumatoid arthritis

25 Jul 2024

Abstract excerpt

BACKGROUND AND OBJECTIVES: The type I interferon (IFN) signature has been found to be overactivated in many systemic autoimmune diseases. This may be explained by impaired regulation of interferon-stimulated genes (ISGs) as well as interferon-induced protein 44 (IFI44) expression via their regulatory mechanisms via interferon regulatory factors (IRFs). PATIENTS AND METHODS: This case-control study includes two...

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PMID: 39051937
DOI: 10.1080/15321819.2024.2381524

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