Article
Treatment sequences in EGFR mutant advanced NSCLC.
Lung cancer (Amsterdam, Netherlands) - 1 Aug 2024
Wespiser M, Swalduz A, Pérol M
Abstract excerpt
Common EGFR gene mutations (exon 19 deletion and L858R in exon 21) are the most frequent cause of actionable genomic alterations in non-small cell lung cancer (NSCLC) patients. The introduction of EGFR tyrosine kinase inhibitors (TKIs) as 1st-line treatment of advanced stages of the disease has changed the natural history of the disease and extended survival rates, establishing third generation TKIs as a new...
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