Article
Emerging treatment for advanced lung cancer with EGFR mutation.
Expert opinion on emerging drugs - 1 Jan 2015
Inal Cengiz, Yilmaz Emrullah, Piperdi Bilal, Perez-Soler Roman, Cheng Haiying
Abstract excerpt
INTRODUCTION: Lung cancer is the leading cause of cancer-related death worldwide. It is usually diagnosed at advanced stage for which platinum-based chemotherapy had been the standard approach, although with limited clinical benefits. Discovery of oncogenic EGFR mutations in lung cancer have shifted the treatment paradigm with molecularly targeted therapies. AREAS COVERED: EGFR tyrosine kinase inhibitors (TKIs)...
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