Article
Autoantibodies as putative biomarkers and triggers of cell dysfunctions in systemic sclerosis
24 Jul 2024
Abstract excerpt
PURPOSE OF REVIEW: Antinuclear autoantibodies represent a serological hallmark of systemic sclerosis (SSc), with anticentromere, antitopoisomerase-I, and anti-RNA polymerase III antibodies routinely assessed for diagnosis, clinical subset classification, and prognosis. In addition, an increasing number of autoantibodies have been demonstrated to play a pathogenic role by mediating different SSc manifestations....
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