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Article

Psychological distress following multi-gene panel testing for hereditary breast and ovarian cancer risk.

Journal of genetic counseling - 1 Apr 2025

Carlsson Lindsay, Bedard Philippe L, Kim Raymond H, Metcalfe Kelly

Abstract excerpt

Advances in our understanding of the genetic landscape of hereditary breast and ovarian cancer (HBOC) have led to the clinical adoption of multi-gene panel testing. Panel testing introduces new sources of genetic uncertainty secondary to the inclusion of moderate- and low-penetrance genes, as well as the increased likelihood of identifying a variant of uncertain significance (VUS). This cross-sectional study...

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Source

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Identifiers

PMID: 39044246
DOI: 10.1002/jgc4.1940
PMCID: PMC11907178

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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