Article
Impact of Panel Gene Testing for Hereditary Breast and Ovarian Cancer on Patients.
Journal of genetic counseling - 1 Oct 2017
Lumish Heidi S, Steinfeld Hallie, Koval Carrie, Russo Donna, Levinson Elana, Wynn Julia, Duong James, Chung Wendy K
Abstract excerpt
Recent advances in next generation sequencing have enabled panel gene testing, or simultaneous testing for mutations in multiple genes for a clinical condition. With more extensive and widespread genetic testing, there will be increased detection of genes with moderate penetrance without established clinical guidelines and of variants of uncertain significance (VUS), or genetic variants unknown to either be...
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