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Article

Subunit Approach to Evaluation of the Immune Protective Potential of Leptospiral Antigens

27 Oct 2011

Abstract excerpt

Leptospirosis is the most widespread zoonosis in the world. Current vaccines are based on whole-cell preparations that cause severe side effects and do not induce satisfactory immunity. In light of the leptospiral genome sequences recently made available, several studies aimed at identification of protective recombinant immunogens have been performed; however, few such immunogens have been identified. The aim of...

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PMID: 22030369
DOI: 10.1128/cvi.05297-11

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