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Article

Assessing the lack of diversity in genetics research across neurodegenerative diseases: A systematic review of the GWAS Catalog and literature.

Alzheimer's & dementia : the journal of the Alzheimer's Association - 1 Aug 2024

Jonson Caroline, Levine Kristin S, Lake Julie, Hertslet Linnea, Jones Lietsel, Patel Dhairya, Kim Jeff, Bandres-Ciga Sara, Terry Nancy, Mata Ignacio F, Blauwendraat Cornelis, Singleton Andrew B, Nalls Mike A, Yokoyama Jennifer S, Leonard Hampton L

Abstract excerpt

The under-representation of non-European cohorts in neurodegenerative disease genome-wide association studies (GWAS) hampers precision medicine efforts. Despite the inherent genetic and phenotypic diversity in these diseases, GWAS research consistently exhibits a disproportionate emphasis on participants of European ancestry. This study reviews GWAS up to 2022, focusing on non-European or multi-ancestry...

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Identifiers

PMID: 39030740
DOI: 10.1002/alz.13873
PMCID: PMC11350004

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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