Article
Genetic testing in early-onset atrial fibrillation.
European heart journal - 7 Sept 2024
Kany Shinwan, Jurgens Sean J, Rämö Joel T, Christophersen Ingrid E, Rienstra Michiel, Chung Mina K, Olesen Morten S, Ackerman Michael J, McNally Elizabeth M, Semsarian Christopher, Schnabel Renate B, Wilde Arthur A M, Benjamin Emelia J, Rehm Heidi L, Kirchhof Paulus, Bezzina Connie R, Roden Dan M, Shoemaker M Benjamin, Ellinor Patrick T
Abstract excerpt
Atrial fibrillation (AF) is a globally prevalent cardiac arrhythmia with significant genetic underpinnings, as highlighted by recent large-scale genetic studies. A prominent clinical and genetic overlap exists between AF, heritable ventricular cardiomyopathies, and arrhythmia syndromes, underlining the potential of AF as an early indicator of severe ventricular disease in younger individuals. Indeed, several...
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