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Clinical and molecular characteristics of patients with brain metastasis secondary to pancreatic ductal adenocarcinoma.

The oncologist - 17 Jan 2025

Yousef Mahmoud, Hurd Mark W, Yousef Abdelrahman, Ludmir Ethan B, Pillai Ashwathy B, Peterson Jennifer, Koay Eugene J, Albarouki Sali, Tzeng Ching-Wei, Snyder Rebecca, Katz Matthew H G, Wang Huamin, Overman Michael J, Maitra Anirban, Pant Shubham, Smaglo Brandon G, Wolff Robert A, Yao James, Shen John P, Zhao Dan

Abstract excerpt

BACKGROUND: The prognosis for patients with pancreatic ductal adenocarcinoma (PDAC) is poor. Secondary brain metastasis (Br-M) occurs in less than 1% of patients. Clinical characteristics and molecular alterations have not been characterized in this rare patients' subset. MATERIALS AND METHODS: The Foundry software platform was used to retrospectively query electronic health records for patients with Br-M...

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Identifiers

PMID: 39014543
DOI: 10.1093/oncolo/oyae182
PMCID: PMC11783327

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KRAS

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