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PSMC2/CCND1 axis promotes development of ovarian cancer through regulating cell growth, apoptosis and migration

22 Jul 2021

Abstract excerpt

Ovarian cancer is known as one of the most common malignancies of the gynecological system, whose treatment is still not satisfactory because of the unclear understanding of molecular mechanism. PSMC2 is an essential component of 19 S regulatory granules in 26 S proteasome and its relationship with ovarian cancer is still not clear. In this study, we found that PSMC2 was upregulated in ovarian cancer tissues,...

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PMID: 34294689
DOI: 10.1038/s41419-021-03981-5

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