Influence of the CYP1A2 c.-163 A > C polymorphism in the effect of caffeine on fat oxidation during exercise: a pilot randomized, double-blind, crossover, placebo-controlled trial.

doi:10.1007/s00394-024-03454-3

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Article

Influence of the CYP1A2 c.-163 A > C polymorphism in the effect of caffeine on fat oxidation during exercise: a pilot randomized, double-blind, crossover, placebo-controlled trial.

European journal of nutrition - 1 Oct 2024

Varillas-Delgado David, Coso Juan Del, Muñoz Alejandro, Aguilar-Navarro Millán, Gutierrez-Hellin Jorge

Abstract excerpt

PURPOSE: The aim of this study was to determine the influence of the CYP1A2 c.-163 A > C (rs762551) polymorphism on the effect of oral caffeine intake on fat oxidation during exercise. METHODS: Using a pilot randomized, double-blind, crossover, placebo-controlled trial, 32 young and healthy individuals (women = 14, men = 18) performed an incremental test on a cycle ergometer with 3-min stages at workloads from 30...

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PMID: 39007997
DOI: 10.1007/s00394-024-03454-3

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