CYP1A2 Genotype and the Ergogenic Effect of Acute Caffeine Intake on Muscular Strength and Endurance Performance in Trained Individuals.

doi:10.1111/sms.70214

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CYP1A2 Genotype and the Ergogenic Effect of Acute Caffeine Intake on Muscular Strength and Endurance Performance in Trained Individuals.

Scandinavian journal of medicine & science in sports - 1 Feb 2026

Montalvo-Alonso Juan Jesús, Del Val-Manzano Marta, Martín-Rivas Iván, Ferragut Carmen, Valadés David, Pérez-López Alberto

Abstract excerpt

This study examined whether CYP1A2 (rs762551) genotype modulates the acute ergogenic effects of caffeine on muscular strength and endurance performance in resistance-trained men and women. Ninety-four resistance-trained participants (47 females, 47 males; 39 AA, 44 AC, 11 CC) completed a randomized, triple-blind, placebo-controlled, crossover trial. Participants ingested 3 mg/kg of caffeine or placebo before...

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PMID: 41627185
DOI: 10.1111/sms.70214
PMCID: PMC12863236

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CYP1A2

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

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