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Article

Novel insights on caffeine supplementation, CYP1A2 genotype, physiological responses and exercise performance.

European journal of applied physiology - 1 Mar 2021

Barreto Gabriel, Grecco Beatriz, Merola Pietro, Reis Caio Eduardo Gonçalves, Gualano Bruno, Saunders Bryan

Abstract excerpt

Caffeine is a popular ergogenic aid due to its primary physiological effects that occur through antagonism of adenosine receptors in the central nervous system. This leads to a cascade of physiological reactions which increases focus and volition, and reduces perception of effort and pain, contributing to improved exercise performance. Substantial variability in the physiological and performance response to acute...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 33403509
DOI: 10.1007/s00421-020-04571-7

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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