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Long non-coding RNA NORAD suppresses erastin-induced ferroptosis in breast cancer by upregulating SLC7A11 via targeting the FUS/NR3C1 axis: experimental studies

20 May 2025

Abstract excerpt

BACKGROUND: Ferroptosis, an iron-dependent cell death, has been widely reported to impede the progression of various malignancies, including breast cancer (BC). Previous evidence has indicated that high expression of non-coding RNA activated by DNA damage (NORAD) is correlated with poor prognosis in BC patients. Nonetheless, it is unclear whether NORAD plays a role in the ferroptosis of BC cells. METHODS: BC...

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PMID: 40405780
DOI: 10.1097/js9.0000000000002531

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