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The role of m6A methylation in targeted therapy resistance in lung cancer

1 Jan 2024

Abstract excerpt

Targeted therapies have greatly improved clinical outcomes for patients with lung cancer (LC), but acquired drug resistance and disease relapse inevitably occur. Increasingly, the role of epigenetic mechanisms in driving acquired drug resistance is appreciated. In particular, N6-methyladenosine (m6A), one of the most prevalent RNA modifications, has several roles regulating RNA stability, splicing, transcription,...

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PMID: 39005690
DOI: 10.62347/lxos2662

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