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Article

eHSP90α in front-line therapy in EGFR exon 19 deletion and 21 Leu858Arg mutations in advanced lung adenocarcinoma.

BMC cancer - 12 Jul 2024

Bian Yingzhen, Liu Haizhou, Huang Jinglei, Feng Zhaorong, Lin Yanyan, Li Jilin, Zhang Litu

Abstract excerpt

PURPOSE: Extracellular heat shock protein 90 AA1(eHSP90α) is intricately linked to tumor progression and prognosis. This study aimed to investigate the difference in the value of eHSP90α in post-treatment response assessment and prognosis prediction between exon 19 deletion(19DEL) and exon 21 Leu858Arg(L858R) mutation types in lung adenocarcinoma(LUAD). METHODS: We analyzed the relationship between the expression...

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Identifiers

PMID: 38997622
DOI: 10.1186/s12885-024-12573-3
PMCID: PMC11245848

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