Article
The BDNF Val66Met polymorphism and health-related quality of life in youth with obesity.
Physiological reports - 1 Jul 2024
Goldfield Gary S, Cameron Jameason D, Sigal Ronald J, Kenny Glen P, Prud'homme Denis, Ngu Mathew, Alberga Angela S, Doucette Steve, Goldfield Diana B, Tulloch Heather, Thai Helen, Simas Kevin R, Walsh Jeremy
Abstract excerpt
The brain derived-neurotrophic factor (BDNF) Val66Met polymorphism causes functional changes in BDNF, and is associated with obesity and some psychiatric disorders, but its relationship to health-related quality of life (HRQoL) remains unknown. This study examined, in youth with obesity, whether carriers of the BDNF Val66met polymorphism Met-alleles (A/A or G/A) differed from noncarriers (G/G) on HRQoL. The...
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