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Article

BDNF Val66Met polymorphism is associated with body mass index in healthy adults.

Neuropsychobiology - 1 Jan 2006

Gunstad John, Schofield Peter, Paul Robert H, Spitznagel Mary Beth, Cohen Ronald A, Williams Leanne M, Kohn Michael, Gordon Evian

Abstract excerpt

Although recent studies suggest a possible relationship between the brain-derived neurotrophic factor Val66Met polymorphism and eating disorders, no study has examined the possibility that the Met-Met genotype is associated with a lower body mass index (BMI) in healthy individuals. We examined this possibility in 481 adults (age range 18-82 years) without significant medical or psychiatric history. After...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 16707914
DOI: 10.1159/000093341

Genes

BDNF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

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BDNF Val66Met polymorphism is associated with body mass index in healthy adults.PMID 16707914Read ↗

Lack of association between brain-derived neurotrophic factor Val66Met polymorphism and body mass index change over time in healthy adults.Semantic proximity Read ↗

The BDNF Val66Met polymorphism serves as a potential marker of body weight in patients with psychiatric disordersSemantic proximity Read ↗

Two British women studies replicated the association between the Val66Met polymorphism in the brain-derived neurotrophic factor (BDNF) and BMI.Semantic proximity Read ↗

Association of the BDNF Val66Met polymorphism with BMI in chronic schizophrenic patients and healthy controls.Semantic proximity Read ↗

Association of the BDNF Val66Met variation with obesity in women.Semantic proximity Read ↗

Recapitulation of the association of the Val66Met polymorphism of BDNF gene with BMI in Koreans.Semantic proximity Read ↗

A protective effect of the BDNF Met/Met genotype in obesity in healthy Caucasian subjects but not in patients with coronary heart disease.Semantic proximity Read ↗

Association between brain-derived neurotrophic factor Val66Met and obesity in children and adolescents.Semantic proximity Read ↗

The BDNF gene Val66Met polymorphism as a modifier of psychiatric disorder susceptibility: progress and controversy.Semantic proximity Read ↗

BDNF Val66Met polymorphism alters food intake and hypothalamic BDNF expression in mice.Semantic proximity Read ↗

The brain-derived neurotrophic factor (BDNF) Val66Met polymorphism is associated with increased body mass index and insulin resistance measures in bipolar disorder and schizophrenia.Semantic proximity Read ↗

BDNF Val66Met polymorphism, energy intake and BMI: a follow-up study in schoolchildren at risk of eating disorders.Semantic proximity Read ↗

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