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Article

Epigenetics in Cardiac Fibrosis

1 Oct 2018

Abstract excerpt

Chemical modifications to nucleosomal DNA and histone tails greatly influence transcription of adjacent and distant genes, a mode of gene regulation referred to as epigenetic control. Here, the authors summarize recent findings that have illustrated crucial roles for epigenetic regulatory enzymes and reader proteins in the control of cardiac fibrosis. Particular emphasis is placed on epigenetic regulation of...

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Identifiers

PMID: 30456341
DOI: 10.1016/j.jacbts.2018.05.003

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