Article
A complete chromosome substitution mapping panel reveals genome-wide epistasis in Arabidopsis.
Heredity - 1 Sept 2024
Wijnen Cris L, Botet Ramon, van de Belt José, Deurhof Laurens, de Jong Hans, de Snoo C Bastiaan, Dirks Rob, Boer Martin P, van Eeuwijk Fred A, Wijnker Erik, Keurentjes Joost J B
Abstract excerpt
Chromosome substitution lines (CSLs) are tentatively supreme resources to investigate non-allelic genetic interactions. However, the difficulty of generating such lines in most species largely yielded imperfect CSL panels, prohibiting a systematic dissection of epistasis. Here, we present the development and use of a unique and complete panel of CSLs in Arabidopsis thaliana, allowing the full factorial analysis...
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