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Article

Predictive modeling of gene mutations for the survival outcomes of epithelial ovarian cancer patients.

PloS one - 1 Jan 2024

Ma Mirielle C, Lavi Ethan S, Altwerger Gary, Lin Z Ping, Ratner Elena S

Abstract excerpt

Epithelial ovarian cancer (EOC) has a low overall survival rate, largely due to frequent recurrence and acquiring resistance to platinum-based chemotherapy. EOC with homologous recombination (HR) deficiency has increased sensitivity to platinum-based chemotherapy because platinum-induced DNA damage cannot be repaired. Mutations in genes involved in the HR pathway are thought to be strongly correlated with...

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Share to Carcinoma, Ovarian Epithelial
Share to Fanconi Anemia Complementation Group Proteins

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Neoplasms, Glandular and Epithelial

Share to Ovarian Neoplasms

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Source

Open in PubMed Open full text

Identifiers

PMID: 38976671
DOI: 10.1371/journal.pone.0305273
PMCID: PMC11230535

Genes

BRCA1
BRIP1
CSMD3
FANCD2
FANCE
FOXM1
KRAS
NBN
PMS2
PTEN
RAD50
TTN

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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