Article
Generation of functionally active resident macrophages from adipose tissue by 3D cultures.
Frontiers in immunology - 1 Jan 2024
Arlat Adèle, Renoud Marie-Laure, Nakhle Jean, Thomas Miguel, Fontaine Jessica, Arnaud Emmanuelle, Dray Cédric, Authier Hélène, Monsarrat Paul, Coste Agnès, Casteilla Louis, Ousset Marielle, Cousin Béatrice
Abstract excerpt
Introduction: Within adipose tissue (AT), different macrophage subsets have been described, which played pivotal and specific roles in upholding tissue homeostasis under both physiological and pathological conditions. Nonetheless, studying resident macrophages in-vitro poses challenges, as the isolation process and the culture for extended periods can alter their inherent properties. Methods: Stroma-vascular...
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