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A Genome-Wide Association Study Suggests New Susceptibility Loci for Primary Antiphospholipid Syndrome.

Arthritis & rheumatology (Hoboken, N.J.) - 1 Nov 2024

Casares-Marfil Desiré, Martínez-Bueno Manuel, Borghi Maria Orietta, Pons-Estel Guillermo, Reales Guillermo, Zuo Yu, Espinosa Gerard, Radstake Timothy, van den Hoogen Lucas L, Wallace Chris, Guthridge Joel, James Judith A, Cervera Ricard, Meroni Pier Luigi, Martin Javier, Knight Jason S, Alarcón-Riquelme Marta E, Sawalha Amr H

Abstract excerpt

OBJECTIVE: Primary antiphospholipid syndrome (PAPS) is a rare autoimmune disease characterized by the presence of antiphospholipid antibodies and the occurrence of thrombotic events and pregnancy complications. Our study aimed to identify novel genetic susceptibility loci associated with PAPS. METHODS: We performed a genome-wide association study comprising 5,485 individuals (482 affected individuals) of European...

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Identifiers

PMID: 38973605
DOI: 10.1002/art.42947
PMCID: PMC11521773

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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