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Elucidating genetic and molecular basis of altered higher-order brain structure-function coupling in major depressive disorder

4 Jul 2024

Abstract excerpt

Previous studies have shown that major depressive disorder (MDD) patients exhibit structural and functional impairments, but few studies have investigated changes in higher-order coupling between structure and function. Here, we systematically investigated the effect of MDD on higher-order coupling between structural connectivity (SC) and functional connectivity (FC). Each brain region was mapped into embedding...

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PMID: 38971483
DOI: 10.1016/j.neuroimage.2024.120722

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