Nanophotonic waveguide-based sensing of circulating cell-free mitochondrial DNA: implications for personalized medicine.

Abstract excerpt

Circulating cell-free mitochondrial DNA (ccf-mtDNA) has emerged as a promising biomarker, with potential implications for disease diagnosis. Changes in mtDNA, such as deletions, mutations or variations in the number of copies, have been associated with mitochondrial disorders, heart diseases, cancer and age-related non-communicable diseases. Previous methods, such as polymerase chain reaction-based approaches,...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Cell-Free Nucleic Acids
• Share to DNA, Mitochondrial