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Article

Investigating druggable kinases for targeted therapy in retinoblastoma.

Journal of human genetics - 1 Sept 2024

Jeyaprakash Kumar, Kumaran Manojkumar, Kim Usha, Santhi Radhakrishnan, Muthukkaruppan Veerappan, Devarajan Bharanidharan, Vanniarajan Ayyasamy

Abstract excerpt

Retinoblastoma (RB) is a childhood retinal neoplasm and commonly treated with cytotoxic chemotherapeutic agents. However, these therapeutic approaches often lead to diverse adverse effects. A precise molecular therapy will alleviate these side effects and offer better treatment outcomes. Over the years, kinases have become potential drug targets in cancer therapy. Hence, we aimed to investigate genetic...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 38956221
DOI: 10.1038/s10038-024-01267-0

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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