Article
Erlotinib or Gefitinib for Treating Advanced Epidermal Growth Factor Receptor Mutation-Positive Lung Cancer in Aotearoa New Zealand: Protocol for a National Whole-of-Patient-Population Retrospective Cohort Study and Results of a Validation Substudy.
JMIR research protocols - 2 Jul 2024
Aye Phyu Sin, Barnes Joanne, Laking George, Cameron Laird, Anderson Malcolm, Luey Brendan, Delany Stephen, Harris Dean, McLaren Blair, Brenman Elliott, Wong Jayden, Lawrenson Ross, Arendse Michael, Tin Tin Sandar, Elwood Mark, Hope Philip, McKeage Mark James
Abstract excerpt
BACKGROUND: Starting in 2010, the epidermal growth factor receptor (EGFR) kinase inhibitors erlotinib and gefitinib were introduced into routine use in Aotearoa New Zealand (NZ) for treating advanced lung cancer, but their impact in this setting is unknown. OBJECTIVE: The study described in this protocol aims to understand the effectiveness and safety of these new personalized lung cancer treatments and the...
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