Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

UBE2C-induced crosstalk between mono- and polyubiquitination of SNAT2 promotes lymphatic metastasis in bladder cancer

30 Jun 2024

Abstract excerpt

Ubiquitination plays an essential role in protein stability, subcellular localization, and interactions. Crosstalk between different types of ubiquitination results in distinct biological outcomes for proteins. However, the role of ubiquitination-related crosstalk in lymph node (LN) metastasis and the key regulatory factors controlling this process have not been determined. Using high-throughput sequencing, we...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Bladder and Urothelial Cancer Treatments
Share to Cancer, Hypoxia, and Metabolism
Share to Ubiquitin and proteasome pathways

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 38949026
DOI: 10.1172/jci179122

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

UBE2C-induced crosstalk between mono- and polyubiquitination of SNAT2 promotes lymphatic metastasis in bladder cancerPMID 38949026Read ↗

UBE2S interacting with TRIM21 mediates the K11-linked ubiquitination of LPP to promote the lymphatic metastasis of bladder cancerSemantic proximity Read ↗

ZRANB1 promotes cell proliferation and lymph node metastasis through SF3B3-mediated alternative splicing of CHEK2 in urothelial bladder cancerSemantic proximity Read ↗

Bioinformatics-based pan-cancer analysis of UBE2CSemantic proximity Read ↗

A Comprehensive Bioinformatics Analysis of UBE2C in CancersSemantic proximity Read ↗

E3 ubiquitin ligases and deubiquitinases in bladder cancer tumorigenesis and implications for immunotherapiesSemantic proximity Read ↗

Ubiquitination in cancer: mechanisms and therapeutic opportunitiesSemantic proximity Read ↗

Long noncoding RNA BLACAT2 promotes bladder cancer–associated lymphangiogenesis and lymphatic metastasisSemantic proximity Read ↗

The APC/C E3 ligase subunit ANAPC11 mediates FOXO3 protein degradation to promote cell proliferation and lymph node metastasis in urothelial bladder cancerSemantic proximity Read ↗

STAMBP-Mediated K63 Deubiquitination of E2F1 Release E2F1 from RB Repressive Complex to Drive Bladder Cancer ProgressionSemantic proximity Read ↗

UBE2M promotes malignant phenotypes of prostate cancer through mediating NAA10 neddylation.Semantic proximity Read ↗

Roles of Ubiquitination and SUMOylation on Prostate Cancer: Mechanisms and Clinical ImplicationsSemantic proximity Read ↗

Ubiquitin-like protein FAT10 promotes bladder cancer progression by stabilizing survivinSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.