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Article

FAM83A is amplified and promotes cancer stem cell-like traits and chemoresistance in pancreatic cancer

13 Mar 2017

Abstract excerpt

Cancer stem cells (CSCs), also known as tumor-initiating cells (TICs), contribute to tumorigenesis, resistance to chemoradiotherapy and recurrence in human cancers, suggesting targeting CSCs may represent a potential therapeutic strategy. In the current study, we found family with sequence similarity 83, member A (FAM83A) is significantly overexpressed and associated with poorer overall survival and disease-free...

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PMID: 28287611
DOI: 10.1038/oncsis.2017.3

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