Article
Immunoinformatics approach for designing a multiepitope subunit vaccine against porcine epidemic diarrhea virus genotype IIA spike protein.
Open veterinary journal - 1 May 2024
Sira Ella Mae Joy S, Banico Edward C, Odchimar Nyzar Mabeth O, Fajardo Lauren Emily, Fremista Ferdinand F, Refuerzo Hanna Angelika B, Dictado Ana Patrisha A, Orosco Fredmoore L
Abstract excerpt
Background: Porcine epidemic diarrhea (PED), caused by the porcine epidemic diarrhea virus (PEDV), is associated with high mortality and morbidity rates, especially in neonatal pigs. This has resulted in significant economic losses for the pig industry. PEDV genotype II-based vaccines were found to confer better immunity against both heterologous and homologous challenges; specifically, spike (S) proteins, which...
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