Article
Strong isolation by distance and evidence of population microstructure reflect ongoing Plasmodium falciparum transmission in Zanzibar.
eLife - 27 Jun 2024
Connelly Sean V, Brazeau Nicholas F, Msellem Mwinyi, Ngasala Billy E, Aydemir Ozkan, Goel Varun, Niaré Karamoko, Giesbrecht David J, Popkin-Hall Zachary R, Hennelly Chris, Park Zackary, Moormann Ann M, Ong'echa John M, Verity Robert, Mohammed Safia, Shija Shija J, Mhamilawa Lwidiko E, Morris Ulrika, Mårtensson Andreas, Lin Jessica T, Björkman Anders, Juliano Jonathan J, Bailey Jeffrey A
Abstract excerpt
Background: The Zanzibar archipelago of Tanzania has become a low-transmission area for Plasmodium falciparum. Despite being considered an area of pre-elimination for years, achieving elimination has been difficult, likely due to a combination of imported infections from mainland Tanzania and continued local transmission. Methods: To shed light on these sources of transmission, we applied highly multiplexed...
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