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Article

The Evolving Scenario of ES-SCLC Management: From Biology to New Cancer Therapeutics.

Genes - 27 May 2024

Trillo Aliaga Pamela, Del Signore Ester, Fuorivia Valeria, Spitaleri Gianluca, Asnaghi Riccardo, Attili Ilaria, Corvaja Carla, Carnevale Schianca Ambra, Passaro Antonio, de Marinis Filippo

Abstract excerpt

Small cell lung cancer (SCLC) is an aggressive neuroendocrine carcinoma accounting for 15% of lung cancers with dismal survival outcomes. Minimal changes in therapy and prognosis have occurred in SCLC for the past four decades. Recent progress in the treatment of extensive-stage disease (ES-SCLC) has been marked by incorporating immune checkpoint inhibitors (ICIs) into platinum-based chemotherapy, leading to...

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Identifiers

PMID: 38927637
DOI: 10.3390/genes15060701
PMCID: PMC11203015

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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