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Article

KRASFormer: a fully vision transformer-based framework for predictingKRASgene mutations in histopathological images of colorectal cancer.

Biomedical physics & engineering express - 17 Jul 2024

Singh Vivek Kumar, Makhlouf Yasmine, Sarker Md Mostafa Kamal, Craig Stephanie, Baena Juvenal, Greene Christine, Mason Lee, James Jacqueline A, Salto-Tellez Manuel, O'Reilly Paul, Maxwell Perry

Abstract excerpt

Detecting the Kirsten Rat Sarcoma Virus (KRAS) gene mutation is significant for colorectal cancer (CRC) patients. TheKRASgene encodes a protein involved in the epidermal growth factor receptor (EGFR) signaling pathway, and mutations in this gene can negatively impact the use of monoclonal antibodies in anti-EGFR therapy and affect treatment decisions. Currently, commonly used methods like next-generation...

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PMID: 38925106
DOI: 10.1088/2057-1976/ad5bed

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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