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Advancements in Hematopoietic Stem Cell Gene Therapy: A Journey of Progress for Viral Transduction

15 Jun 2024

Abstract excerpt

Hematopoietic stem cell (HSC) transduction has undergone remarkable advancements in recent years, revolutionizing the landscape of gene therapy specifically for inherited hematologic disorders. The evolution of viral vector-based transduction technologies, including retroviral and lentiviral vectors, has significantly enhanced the efficiency and specificity of gene delivery to HSCs. Additionally, the emergence of...

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PMID: 38920667
DOI: 10.3390/cells13121039

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