Article
TWAS facilitates gene-scale trait genetic dissection through gene expression, structural variations, and alternative splicing in soybean.
Plant communications - 14 Oct 2024
Li Delin, Wang Qi, Tian Yu, Lyv Xiangguang, Zhang Hao, Hong Huilong, Gao Huawei, Li Yan-Fei, Zhao Chaosen, Wang Jiajun, Wang Ruizhen, Yang Jinliang, Liu Bin, Schnable Patrick S, Schnable James C, Li Ying-Hui, Qiu Li-Juan
Abstract excerpt
A genome-wide association study (GWAS) identifies trait-associated loci, but identifying the causal genes can be a bottleneck, due in part to slow decay of linkage disequilibrium (LD). A transcriptome-wide association study (TWAS) addresses this issue by identifying gene expression-phenotype associations or integrating gene expression quantitative trait loci with GWAS results. Here, we used self-pollinated...
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