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Article

Integrated analysis of ncRNA in hepatocellular carcinoma with CTNNB1 mutations reveals miR-205-5p and miR-3940-3p Axes.

Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver - 1 Jan 2025

Zhang Haibin, Zhang Guoqing, Lu Siyu, Zhang Xiaolu, Yu Jingya

Abstract excerpt

BACKGROUND: Catenin beta 1 (CTNNB1) mutations are one of the most common mutations involved in hepatocellular carcinoma (HCC) progression. However, the association between CTNNB1 mutations and HCC remains controversial. METHODS: Five tumor samples with wild-type CTNNB1 and three tumor samples with CTNNB1 mutations were collected from patients with HCC for whole transcriptome sequencing. Selected ncRNAs and mRNAs...

Read the complete abstract on PubMed

Topics

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Share to beta Catenin
Share to Carcinoma, Hepatocellular

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Cell Line, Tumor

Share to Gene Expression Regulation, Neoplastic

Share to Liver Neoplasms

Share to MicroRNAs

Share to Mutation

Share to RNA, Untranslated

Source

Identifiers

PMID: 38918127
DOI: 10.1016/j.dld.2024.06.001

Genes

CTNNB1
CES1
GHRHR
GLIS3
LY6E
MATN2
SERPINA5
STAT4
TXNRD1
WNK2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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