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Impact of genetic variants in IL-2RA and IL-2RB on breast cancer risk in Chinese Han women.

Biochemical genetics - 1 Jun 2021

He Lingge, Zhang Wenjie, Yang Shuangyu, Meng Wenting, Dou Xia, Liu Jianfeng, Liu Yuanwei, Li Haiyue, Jin Tianbo

Abstract excerpt

The expression of IL-2RA and IL-2RB was correlated with breast cancer (BC) progression. However, there is no literature investigating the association of IL-2RA and IL-2RB polymorphisms with BC predisposition among Chinese Han Women. Seven SNPs in IL-2RA and IL-2RB were genotyped by Agena MassARRAY platform among 553 BC patients and 550 healthy controls. Odds ratios (OR) and 95% confidence interval (CI) adjusted...

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PMID: 33507447
DOI: 10.1007/s10528-021-10029-y

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