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Article

Contrasting Phenotypes of Neutrophils During Asymptomatic Versus Symptomatic Leishmania braziliensis Infection.

The Journal of infectious diseases - 16 Dec 2024

Conceição Jacilara A, Carneiro Pedro P, Dórea Andreza S, Oliveira Walker N, Muniz Aline C, Carvalho Edgar M, Wilson Mary E, Bacellar Olívia

Abstract excerpt

BACKGROUND: The mechanisms that mediate immune protection in individuals with subclinical (SC) or asymptomatic infection with Leishmania braziliensis are largely unknown. Neutrophils (polymorphonuclear leukocytes [PMNs]) have been implicated in progressive symptomatic cutaneous leishmaniasis (CL), but their potential participation in maintenance of subclinical infection is unexplored. The aim of this study was to...

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Identifiers

PMID: 38912968
DOI: 10.1093/infdis/jiae317
PMCID: PMC11646601

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