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Comparative genomic sequencing to characterize Mycoplasma pneumoniae genome, typing, and drug resistance.

Microbiology spectrum - 6 Aug 2024

Jiang Yue, Kang Hailong, Dou Haiwei, Guo Dongxing, Yuan Qing, Dong Lili, Du Zhenglin, Zhao Wenming, Xin Deli

Abstract excerpt

To analyze the characteristics of Mycoplasma pneumoniae as well as macrolide antibiotic resistance through whole-genome sequencing and comparative genomics. Thirteen clinical strains isolated from 2003 to 2019 were selected, 10 of which were resistant to erythromycin (MIC >64 µg/mL), including 8 P1-type I and 2 P1-type II. Three were sensitive (<1 µg/mL) and P1-type II. One resistant strain had an A→G point...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 38904371
DOI: 10.1128/spectrum.03615-23
PMCID: PMC11302288

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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