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Article

Application value of multi-gene mutation detection in the clinical management of pediatric papillary thyroid carcinoma: a preliminary exploration.

Frontiers in endocrinology - 1 Jan 2024

Wang Yuguo, Wang Hui, Tan Gongxun, Wu Xinping, Wang Bin, Tan Zhihan, Du Jing, Li Xiuying, Xu Ying, Yan Na, Qian Xiaoqin

Abstract excerpt

Objectives: Thyroid cancer rarely occurs in children and adolescents. Molecular markers such as BRAF, RAS, and RET/PTC have been widely used in adult PTC. It is currently unclear whether these molecular markers have equivalent potential for application in pediatric patients. This study aims to explore the potential utility of a multi-gene conjoint analysis based on next-generation targeted sequencing for...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 38904052
DOI: 10.3389/fendo.2024.1405142
PMCID: PMC11188297

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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