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The multifaceted roles of selective autophagy receptors in viral infections

30 Aug 2024

Abstract excerpt

Selective autophagy is a protein clearance mechanism mediated by evolutionarily conserved selective autophagy receptors (SARs), which specifically degrades misfolded, misassembled, or metabolically regulated proteins. SARs help the host to suppress viral infections by degrading viral proteins. However, viruses have evolved sophisticated mechanisms to counteract, evade, or co-opt autophagic processes, thereby...

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PMID: 39212450
DOI: 10.1128/jvi.00814-24

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