Effects of caffeine on ultraviolet-induced base-pair substitution and frameshift mutagenesis in Salmonella.

doi:10.1016/0165-7992(85)90095-8

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Article

Effects of caffeine on ultraviolet-induced base-pair substitution and frameshift mutagenesis in Salmonella.

Mutation research - 1 Jan 2000

MacPhee D G, Leyden M F

Abstract excerpt

Using an excision-deficient, di-auxotrophic, strain of Salmonella typhimurium we have shown that caffeine significantly inhibits the formation of ultraviolet-induced base-pair substitution mutations, but has only a marginal effect on the formation of frameshift mutations in the same population of...

Topics

Caffeine
DNA Repair
Mutagenicity Tests
Mutation
Salmonella typhimurium
Templates, Genetic
Ultraviolet Rays

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