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Article

Toxicities from BRAF and MEK Inhibitors: Strategies to Maximize Therapeutic Success.

Current oncology reports - 1 Aug 2024

Wang Mike, Sullivan Ryan J, Mooradian Meghan J

Abstract excerpt

PURPOSE OF REVIEW: This report highlights several of the recent therapeutic advancements in the treatment of BRAF-mutant tumors, discusses the most common adverse events observed with BRAF-targeted agents, and suggests strategies to manage and mitigate treatment-related toxicities. RECENT FINDINGS: BRAF and MEK inhibitors represent a significant advancement in the treatment of BRAF-mutated malignancies with data...

Topics

Humans
Proto-Oncogene Proteins B-raf
Protein Kinase Inhibitors
Neoplasms
Mutation
Antineoplastic Agents
Mitogen-Activated Protein Kinase Kinases
Molecular Targeted Therapy

Source

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Identifiers

PMID: 38850505
DOI: 10.1007/s11912-024-01544-3

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

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