Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Whole-exome sequencing-based mutational profiling of hepatocellular adenoma malignant transformation to hepatocellular carcinoma.

Clinical and experimental pharmacology & physiology - 1 Jul 2024

Bu Yichao, Huang Run, Gao Jun, Qu Weifeng, Fu Xiutao, Liu Weiren, Ding Zhenbin, Zhou Jian, Fan Jia, Wang Xin, Chen Diyu, Tang Zheng

Abstract excerpt

Hepatocellular adenoma (HCA) represents a rare benign hepatic neoplasm with potential for malignant transformation into hepatocellular carcinoma (HCC), yet the underlying mechanism remains elusive. In this study, we investigated the genomic landscape of this process to identify therapeutic strategies for blocking malignant transformation. Using micro-detection techniques, we obtained specimens of adenoma,...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Adenoma, Liver Cell
Share to Carcinoma, Hepatocellular

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Cell Transformation, Neoplastic

Share to DNA Copy Number Variations

Share to DNA Mutational Analysis

Share to Exome Sequencing

Share to Liver Neoplasms

Share to Mutation

Source

Identifiers

PMID: 38843867
DOI: 10.1111/1440-1681.13901

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Whole-exome sequencing-based mutational profiling of hepatocellular adenoma malignant transformation to hepatocellular carcinoma.PMID 38843867Read ↗

Exome analysis of the evolutionary path of hepatocellular adenoma-carcinoma transition, vascular invasion and brain dissemination.Semantic proximity Read ↗

Characterization of hepatocellular adenoma and carcinoma using microRNA profiling and targeted gene sequencingSemantic proximity Read ↗

Novel insights into the molecular heterogeneity of hepatocellular carcinomaSemantic proximity Read ↗

Genomic and transcriptomic somatic alterations of hepatocellular carcinoma in non-cirrhotic liversSemantic proximity Read ↗

Advances in genomic hepatocellular carcinoma researchSemantic proximity Read ↗

The mutational landscape of hepatocellular carcinoma.Semantic proximity Read ↗

Next generation sequencing reveals genetic landscape of hepatocellular carcinomas.Semantic proximity Read ↗

High-resolution characterization of a hepatocellular carcinoma genome.Semantic proximity Read ↗

Functional genomic studies: insights into the pathogenesis of liver cancer.Semantic proximity Read ↗

Genomic analysis of liver cancer unveils novel driver genes and distinct prognostic features.Semantic proximity Read ↗

Somatic HNF1A mutations in the malignant transformation of hepatocellular adenomas: a retrospective analysis of data from MSK-IMPACT and TCGA.Semantic proximity Read ↗

Molecular Pathology of Hepatic Neoplasms: Classification and Clinical SignificanceSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.