Article
A set of circulating microRNAs belonging to the 14q32 chromosome locus identifies two subgroups of individuals with recent-onset type 1 diabetes.
Cell reports. Medicine - 18 Jun 2024
Sebastiani Guido, Grieco Giuseppina Emanuela, Bruttini Marco, Auddino Stefano, Mori Alessia, Toniolli Mattia, Fignani Daniela, Licata Giada, Aiello Elena, Nigi Laura, Formichi Caterina, Fernandez-Tajes Juan, Pugliese Alberto, Evans-Molina Carmella, Overbergh Lut, Tree Timothy, Peakman Mark, Mathieu Chantal, Dotta Francesco
Abstract excerpt
Circulating microRNAs (miRNAs) are linked to the onset and progression of type 1 diabetes mellitus (T1DM), thus representing potential disease biomarkers. In this study, we employed a multiplatform sequencing approach to analyze circulating miRNAs in an extended cohort of prospectively evaluated recent-onset T1DM individuals from the INNODIA consortium. Our findings reveal that a set of miRNAs located within T1DM...
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