Article
Phospholipid metabolism-related genotypes of PLA2R1 and CERS4 contribute to nonobese MASLD.
Hepatology communications - 1 Jun 2024
Shao Congxiang, Ye Junzhao, Dong Zhi, Liao Bing, Feng Shiting, Hu Shixian, Zhong Bihui
Abstract excerpt
BACKGROUND: Abnormal phospholipid metabolism is linked to metabolic dysfunction-associated steatotic liver disease (MASLD) development and progression. We aimed to clarify whether genetic variants of phospholipid metabolism modify these relationships. METHODS: This case-control study consecutively recruited 600 patients who underwent MRI-based proton density fat fraction examination (240 participants with serum...
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