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Article

Distinguishing risk of curve progression in adolescent idiopathic scoliosis with bone microarchitecture phenotyping: a 6-year longitudinal study.

Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research - 5 Aug 2024

Yang Kenneth Guangpu, Lee Wayne Yuk-Wai, Hung Alec Lik-Hang, Kumar Anubrat, Chui Elvis Chun-Sing, Hung Vivian Wing-Yin, Cheng Jack Chun-Yiu, Lam Tsz-Ping, Lau Adam Yiu-Chung

Abstract excerpt

Low bone mineral density and impaired bone quality have been shown to be important prognostic factors for curve progression in adolescent idiopathic scoliosis (AIS). There is no evidence-based integrative interpretation method to analyze high-resolution peripheral quantitative computed tomography (HR-pQCT) data in AIS. This study aimed to (1) utilize unsupervised machine learning to cluster bone microarchitecture...

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Identifiers

PMID: 38832703
DOI: 10.1093/jbmr/zjae083

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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